Cell proliferation induced by GPE was further delineated by an increased level of phosphorylated Akt, indicating potential upregulation of the ERK ( Figure 6 ) and PI3K/Akt signaling pathways ( Figure 7 ) pathways, which are among the signaling pathways involved in the regulation of cell proliferation
Schonleben-Janas A, Kirsch P, Mittl PR, Schirmer RH, Krauth-Siegel RL
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The best binding poses for both substrates had a highly similar conformation to ()-catechin ( 12 ), with an RMSD of matched atoms of 0.51 for flavan-3,3,4-triol ( 4 ) and 0.54 for flavan-3-on-4-ol ( 7 )
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1.11.1.9) is a cytosolic enzyme responsible for the reduction of hydroperoxides