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Orally people can tolerate up to 4 grams usually, but via IV people can do much higher doses

Some remain at 8 mg long-term, while others reach and tolerate 12 mg comfortably

Questions to Ask Your Doctor Given my weight loss goals, is a GLP-1 a good fit for me

Surgery GLP-1 drugs mimic at least one hormone produced by the gut to signal fullness, leading to a reduced appetite

The peptide shares approximately 48% amino acid sequence homology with insulin and binds to insulin receptors, though with lower affinity than insulin itself