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The proline residue at position 14 has been proven to play a crucial role in melittins antibacterial action (Sharma et al., 2024b)

Chowdhury N, Farooq T, Abdullah S, Mahadi A, Hasan M, et al

[PubMed ID: 22197148]

While there's limited research on copper peptides, Murphy-Rose says that it seems to suggest that the ingredient has great benefits for the skin, with little risk of irritation or other adverse effects