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GLP-1 receptor agonists such as semaglutide and tirzepatide-related therapies have strong evidence for diabetes and weight management when used appropriately

A groundbreaking 2019 study demonstrated that colonizing ALS mice with Akkermansia muciniphila (a mucin-degrading bacterium usually considered pro-inflammatory in PD/MS contexts) actually ameliorated ALS progression in the mice [83]

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A, amyloid-beta

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3.5 Others 3.5.1 Berberine Huanglian ( Coptis chinensis Franch., belonging to the Ranunculaceae family) is widely used in the treatment of diabetes, and its bioactive metabolite is mainly berberine