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The PBN receives direct GLP-1 projections from NTS neurons (Richard et al., 2014)

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rather, it reflects disproportion between oxidative demand and the dynamic regeneration of redox currency across tissues

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Crosstalk between adipose remodeling and systemic metabolism The metabolic benefits observed at the whole-body levelincluding improved glucose tolerance, decreased hepatic enzyme levels, and normalization of circulating lipidsare likely secondary to the restoration of adipose tissue function