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The lack of naturally occurring GLP-1 in humans is one of the causes of type 2 diabetes

Linagliptin is rapidly absorbed after oral administration with a T max of 0.73 h that does not differ between healthy and T2DM subjects after single or multiple doses [9092]

Nutrient Requirements during Pregnancy and Lactation

It is an investigational drug in active Phase 3 trials

In major studies, adults with obesity (without diabetes) who took the daily oral formulation achieved an average weight loss of approximately 15% to 17% of their body weight over 68 weeks

In 2017, the FDA approved the drug to treat type 2 diabetes under the brand name Ozempic