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The real key is going to be side effects over time, if retatrutide is like other drugs in the class then the side effects should decrease with time, but unfortunately, we dont have that today, at this point I have some questions and minor concerns but without the data over time its hard to speculate about tolerability further beyond saying its similar to other drugs in the class

In clinical trials, retatrutide has been administered as a once-weekly subcutaneous injection, with a structured dose-escalation schedule used to improve tolerability

It also messed with the way I smell perfumes

DNA Repair Capacity PARP-mediated DNA repair is directly dependent on NAD+ supply

The FDA requires that prescribers of semaglutide counsel women that pregnancy is contraindicated during treatment and for two months after discontinuation [8]

The cost difference is minimal compared to wasted time and money on inactive products