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Moreover, GLP-1RAs can suppress atherosclerosis in T2DM (STZ treated) rats by inhibiting macrophage infiltration and apoptosis [66]

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Tirzepatide is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for the treatment of type 2 diabetes mellitus under the brand name Mounjaro and for chronic weight management as Zepbound

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One year after PCI, researchers observed reductions in MACE, myocardial infarction, and heart failure exacerbation, remaining consistent after one year