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By identifying common dysregulated pathways across these conditions, we can gain insights into the complex pathophysiology underlying symptoms such as fatigue, PEM and postural orthostatic tachycardia syndrome (POTS)

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The proestrus and oestrus of rats in the 3,000 mg/kg/d groups basically disappeared, and the cycle stagnated mostly in meta-oestrus and dioestrus (Figure 4)