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Previous studies from our group demonstrated that GLP-1RAs provide protection against steatohepatitis in high-fat diet (HFD)-induced obese mice [17], and against high phosphate-induced vascular calcificationa hallmark of atherosclerosisthrough AMPK activation [18]

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doi: 10.1016/0090-6980(81)90123-4

& Walker, S

M.SaxtonR

Approximately 21% of the 159 adult patients in the 400 mg/day group who received topiramate as monotherapy in the controlled clinical trial discontinued therapy due to adverse events