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doi: 10.3390/ijms22115717

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Additionally, pirin (PRI), an iron-binding nuclear protein, plays a critical role in nuclear stress during ferroptosis by downregulating ACSL4 mRNA and its product, AA, thereby inhibiting ACSL4-mediated ferroptosis in PDAC [44]

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Drug Interactions Based on clinical potential significance, patients receiving valproic acid require an increased dosage of levocarnitine