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Encourages the buildup of collagen and other structural components of tissue, supporting tissue renewal and repair

Unlike rat-derived systems, minipig subcellular fractions strongly resembled human in vivo metabolism in terms of amide hydrolysis based on the compounds assayed in this study

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In phase 2 trials, cagrilintide alone produced dose-dependent reductions in body weight, with participants on the highest dose (4.5 mg weekly) losing roughly 10-15% of body weight over 26 weeks