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It has been observed that in high doses it can trigger or even worsen outbreaks of acne Conclusion: Vitamin B12 and Acne The exact causes of vitamin B12 acne are still unclear

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Vitamin B12 shot side effects Most people tolerate vitamin B12 injections well, but possible side effects include: Mild: soreness or redness at injection site, mild diarrhea, nausea, headache, itching Rare but serious: allergic reactions (rash, swelling, difficulty breathing), low potassium (hypokalemia), dizziness or heart rate changes Get emergency medical help if you have signs of an allergic reaction to Vitamin B12: hives

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Processed foods are sometimes fortified with B12 to enhance their nutritional value