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Using both SGLT-2 and DPP-4 inhibitors as active comparators strengthened study validity, while register linkage minimized selection and recall bias by ensuring exposures were recorded independently of outcomes

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DL algorithms including ResNet-50 (a deep convolutional neural network that is widely used for image classification, object detection and feature extraction) and adaptive neuro-fuzzy inference systems (a hybrid ML model that combines neural network with fuzzy logic) analyze CNFL in CCM images

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10.1016/0092-8674(91)90098-j 186 ThomasJ