Saxenda has already been approved to treat obesity in Novo Nordisks major markets and has been well received by the target patients
The clinical read-throughs are accumulating: a randomized trial (Hendershot et al., JAMA Psychiatry 2025) showed semaglutide cut drinks per drinking day, heavy drinking days, and cravings (and even cigarettes) versus placebo
These include a products safety, effectiveness, cost, convenience, and in this case taste
2.2 Recommendations for Use in Renal Impairment Assess renal function prior to initiation of JANUMET and periodically thereafter
IM offers convenience
In specific embodiments, any formulation or composition described herein has a pH that allows for terminal sterilization (e.g., by heat treatment and/or autoclaving) of a formulation or composition without degradation of the therapeutic agent