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[DOI] [PMC free article] [PubMed] [Google Scholar] Pawlak 2013 Pawlak R, Parrott SJ, Raj S, CullumDugan D, Lucus D
(PubMed) Shrubsole MJ, Shu XO, Li HL, et al
Eur J Clin Nutr 79 , 607610 (2025)
Additional risk factors include: Chronic kidney disease : Reduced renal clearance may impair B12 excretion Liver disease : Hepatic dysfunction can disrupt B12 metabolism and storage Myeloproliferative disorders : Certain blood cancers increase B12-binding proteins Concurrent medication use : Some drugs may interact with B12 metabolism, including metformin, proton pump inhibitors, and H2 antagonists Patients with these conditions should have B12 supplementation carefully monitored by their healthcare team
The results showcased an average decrease in body fat percentage, particularly around the abdominal area, highlighting its targeted action
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