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In brief, the full-length histones H2A, H2B, H3 and H4 were purified in Escherichia coli strain BL21

Supernatants from stimulated cells or protein standard (N protein standard SL, Siemens) were incubated on the plates at room temperature for 2 h

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Cycling Details The 8-12 week on / 4-8 week off cycle accounts for the absence of long-term human safety data

Pharmacol Res 140:100114 Xin S-H, Tan L, Cao X, Yu J-T, Tan L (2018) Clearance of amyloid beta and tau in Alzheimers disease: from mechanisms to therapy

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