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Published August 16, 2024

Since the late 1800s, doctors have turned to surgery to treat appendicitis

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4-HNE can also bind to nuclear hormone receptors, such as peroxisome proliferator-activated receptor delta (PPAR), promoting the transcription of genes involved in keratinocyte differentiation, such as involucrin and transglutaminase 1, thereby exacerbating epidermal hyperplasia typical of psoriasis [43]

Part of the antioxidant capacity of serum is due to the presence of GSH and the reduced capacity could be associated with a general reduction in GSH due to its conjugation with NAPQI