In randomized controlled trials in people living with HIV and central fat accumulation, tesamorelin produced clinically meaningful reductions in visceral adipose tissue in a majority of patients and was associated with improvements in liver enzymes when deep abdominal fat decreased
Reference: Dimet-Wiley AL, Latham CM, Brightwell CR, Neelakantan H, Keeble AR, Thomas NT, Noehren H, Fry CS, Watowich SJ (2024)
If something feels wrong, it probably is
Women taking oral contraceptives may have decreased serum B 12 levels in the absence of clinical deficiency (due to decreases in the B 12 carrier protein, haptocorrin)
Vitamin B12, when injected, can increase energy, decrease inflammation, improve metabolism, and support sleep, mood, and memory
B12 does not suppress appetite or block fat storage