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We also know that muscle mass naturally declines with age

(PubMed) Michaud DS, Spiegelman D, Clinton SK, Rimm EB, Willett WC, Giovannucci EL

Front Neuroinform

6.3 Incretin Receptor Activation Normalizes Insulin Sensitization Insulin sensitivity in the brain is reduced in several animal models of AD and PD, most likely driven by the chronic inflammation response and the release of proinflammatory cytokines that block growth factor signaling [23, 88, 124,125,126,127]