Adverse Dermatological Effects of GLP-1RAs The administration of GLP-1RAs can lead to various skin reactions that range from injection-site localized responses to serious immune system-triggered conditions such as systemic hypersensitivity reactions (refer to Table 1)
Given these anti-inflammatory effects, there is speculation that GLP-1 medicines could impair host immune defenses
Certain variants of PAM are more common in those with diabetes and may impair the release of insulin from the pancreas
83 Interestingly, EX-QW appears not to have a significant additive effect
102 The latter, glucagon, is a basic glucose-regulating hormone with catabolic and thermogenic actions, but it also increases glucose levels and the risk of gluconeogenesis
But the techies were the first on this because of the willingness to take ridiculous risks. After we reached out with questions, a spokesperson emphasized that Temu is a third-party marketplace for independent sellers to offer products, subject to platform rules and controls. The platform prohibits the sale of products containing peptides listed as bulk drug substances by the US FDA, products making therapeutic or medical claims without proper authorization, and sterile needles or syringes intended for injection, the spokesperson continued
