Published studies demonstrate: Significant TERT upregulation in human somatic cells (WI-38, HEK, diploid fibroblasts) after Epitalon exposure Telomere length preservation in replicatively aged fibroblast cultures (Q-FISH, TRF Southern) Life-span extension in multiple model organisms (Drosophila melanogaster, Ceriodaphnia affinis) in controlled laboratory studies Association with reduced age-related chromosomal instability and aneuploidy in long-term culture models GHK-Cu does not directly activate telomerase and has not been documented to significantly alter telomere length
It seems that the reduction of protein persulfides by dithiols can also occur in other persulfidated proteins
Curcumin demonstrates a substantial ability to interact with and modulate the regulation of various proteins, growth factors, transcription factors, enzymes, receptors, and other regulatory genes through both direct and indirect mechanisms (Goel et al., 2008
Some in vitro studies show increased telomerase activity in human fibroblast cultures exposed to Epithalon
(PubMed) Zimmermann MB, Wegmuller R, Zeder C, Chaouki N, Torresani T
Chirumbolo S, Franzini M, Ricevuti G, Valdenassi L (2025b) Intravenous glutathione should not be mismatched with ozone as an antioxidant therapy
