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These findings remain in early exploratory stages and warrant further rigorous study

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With cytochrome P-450, the substrate is jammed right up against the location where the oxo ligand must reside in the high-valent oxo intermediate

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In view of a clear Vit B12 deficiency and/or HHcy and/or high MMA levels in a PwPD presetting with clinical signs of PN, a complete neurographic assessment and an extensive alternative-causes workup should be performed