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Systemic chronic inflammation was at the center of all of it

First, most of the patients whose records were used for the study were older, White and male, which is typical of the population served by the VA health system

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The dual action of decreasing fat synthesis while increasing fat breakdown represents a coordinated metabolic shift in laboratory models

Joo Pessoa Univ

This mechanism enables macrophages to sustain focal exocytosis and efficiently internalize multiple ACs in sequence, providing a mechanistic explanation for how mitochondrial dynamics support continuous efferocytosis [79]