Always consult your healthcare provider before making treatment decisions.
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Medications like orforglipron (an oral, non-peptide GLP-1 agonist), survodutide (a dual glucagon/GLP-1 agonist), and CagriSema (combining cagrilintide with semaglutide) are advancing through clinical trials
It's important to note that semaglutide is not recommended for patients with severe gastrointestinal disease, including severe gastroparesis, as these conditions have not been studied in clinical trials and may be exacerbated by the medication's effects on gastric emptying
This means retatrutide activates the GIP receptor most aggressively, the GLP-1 receptor at moderate strength, and the glucagon receptor at the lowest level
Since semaglutide affects both appetite and digestion, it can alter how many nutrients a person consumes
