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Compared with normal animals, Nrf2-deficient mice have more pronounced effects on lipopolysaccharide (LPS)-induced microglial activation and inflammatory response, with lower levels of IL-1, IL-6, IL-12, and TNF- in the brain ( Moreover, increasing evidence indicated that Nrf2 may regulate mitochondrial function and metabolism

However, hepatic diseases have become a global epidemic, causing significant burdens

Akt phosphorylation of mitochondrial Lonp1 protease enables oxidative metabolism and advanced tumor traits

Satellite cell preparation and activation assay Satellite cells were isolated from the upper hindlimb and back muscles of 910 month-old male Sprague-Dawley rats according to Allen et al

Tada et al., 2002