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While many wellness peptides influence growth hormone levels or target specific tissue repair, MOTS-C is unique because it originates in the mitochondrial genome
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4 Conclusion In conclusion, due to its multifaceted and heterogeneous nature, a personalized approach is necessary for obesity management, especially in syndromic obesity like PWS where the underlying pathophysiology remains largely unknown
The mechanism likely involved is that catalpol inhibits H 2 O 2 -induced ROS, MDA, Bax, and caspase-9 production while activating SOD, GSH-Px, and Bcl-2 expression (Yan et al., 2020)