The sponsor conducted several scenario analyses on each modelled population, including taking a taking a societal perspective, omitting discounting, increasing the discount rate to 3%, using a 20-year time horizon, changing the threshold for intensification treatment to 8.5% from 8%, and using the number of years associated with the initial treatment as opposed to using hemoglobin A1C as a threshold for intensification (i.e., the intensification trigger threshold was 4 years for second-line treatment and 5 years for third-line treatment)
Christen 2008
Medicare and Medicaid patients typically cannot use manufacturer coupons
After 12 weeks of HFD feeding, Gipr Syn/ mice demonstrated significantly lower body weight (Fig
Reference lists of pertinent papers were also examined to ensure inclusion of additional relevant works
Herbal formulas (such as those listed in Table 1) are commonly used in in various academic centers in the West (such as the Memorial Sloan-Kettering Cancer Center [51], University of California, Los Angeles [52], University of California San Francisco [53], Cleveland Clinic [54], and Cornell University [55])