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These can include an abnormal heart sound during a heartbeat (heart murmur), rapid breathing (tachypnea), low blood pressure (hypotension), low levels of oxygen in the blood (hypoxemia), and a blue or purple tint to the skin caused by a shortage of oxygen (cyanosis)

Based on this analysis, between June and December of this year, it has taken an average of about 20 days for drugs to go from being listed as available to shortages being officially resolved by the FDA

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Antioxidants , 2021

J Biol Chem 285:4152532