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Liniezione SC nel tessuto sottocutaneo (addome, coscia) aggira la digestione e garantisce disponibilit sistemica

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10.1017/S1355617715000673 22 BillingerS

Clin Sci (Lond) 109:243256

369 In the phase 1b trial of AMG-232 monotherapy or trametinib in patients with R/R AML, 370 1 patient had DLT, 31% (4/13) of patients expressing wild-type p53 had a response, and no patients expressing mutant p53 had a response

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