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Through GLP-1R activation, Retatrutide is associated with enhanced glucose-stimulated insulin secretion, delayed gastric emptying, and increased satiety

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Participants on the same dosing level for longer periods generally showed more sustained improvements, reinforcing that retatrutide works cumulatively over time

doi: 10.2337/diacare.27.11.2628 53 ApovianCMBergenstalRMCuddihyRMQuYLenoxSLewisMSet al