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One study reported that the scaffold protein phosphatidylethanolamine binding protein 1 (PEBP1) binds to 15-lipoxygenase (15LOX) and directs it to PUFAs in the membrane, thereby facilitating ferroptosis [81]

10.3389/fmed.2022.813204 168 MoawadM

Tukey pair-wise comparison for both routes indicated a significant difference between highest and lowest doses ( p = 0.046)

A very good example is linagliptin, which is predominantly excreted through the bile rather than through the kidneys

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D, E Detailed GO enrichment analysis of the upregulated DEGs (D) and downregulated DEGs (E)