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The high molecular mass of GLP-1s suggests that transfer across the placenta wouldnt be expected, but given the lack of knowledge, women using them for weight loss (who do not have diabetes) are advised to stop before trying to conceive

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En estudios experimentales de ERD el tratamiento con arGLP-1 se ha asociado con mejoras histolgicas (reduccin de la hipertrofia glomerular, de la expansin mesangial, del engrosamiento de la membrana basal glomerular y del dao tubulointersticial)110,111

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We used the crystallography structures of the extracellular domain of the GLP-1 receptor (PDB ID: 3IOL) and human serum albumin (PDB ID: 1AO6) to enter the docking steps