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Yamagishi S, Nakamura K, Imaizumi T
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Other mechanisms that regulate the intracellular iron abundance, such as the exportation of iron via various multivesicular bodies and exosomes carrying ferroportin or prominin2-mediated ferritin, can also affect the cellular sensitivity to ferroptosis, as they deplete the cellular iron and accelerate the lipid peroxidation (53) ( Figure 1 )
Age-related skeletal muscle mass wasting (also known as sarcopenia) tends to become an issue in elderly individuals, since the bodys ability to regenerate declines with age
Notably, the rate of degradation increases with increasing temperature, whereas the antioxidant activity correspondingly decreases with both elevated temperature and prolonged exposure time
