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Western blot assays showed that no significant alteration in the expression of SLC7A11 was observed in VRK2-downregulating PC cells (Fig

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Room temperature storage of reconstituted peptide causes rapid degradation

The peptide downregulates TNF- (6.2-fold reduction) and IL-6 (4.1-fold reduction) while upregulating anti-inflammatory IL-10 (8.1-fold increase)[12]

Unlike older peptides in its class, it is selective, meaning it does not spike cortisol, prolactin, or hunger hormones in the way some earlier compounds did

Permeability changes have not been verified yet in the constipation-predominant IBS (IBS-C) subgroup by other investigations, whereas patients with mixed bowel habits (IBS-M) have not been investigated so far