No aversion was induced by mutants in earlier or later steps of ECA synthesis, suggesting that accumulation of an inner membrane intermediate, rather than the loss of ECA, drives C
Nature 2021;593:58690
This oxidative burst serves dual roles: while moderate ROS levels activate antiviral signaling, excessive ROS production triggers mitochondrial permeability transition, mtDNA release, and cell death (Kayesh et al., 2025)
So, next time your gut throws a tantrum, think beyond hajmola, probiotics and peppermint tea
[DOI] [PMC free article] [PubMed] [Google Scholar] Forman HJ, Torres M (2002) Reactive oxygen species and cell signaling: respiratory burst in macrophage signaling
10.1016/j.jsbmb.2007.09.011 J