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TNF- and Il-1 Determination The levels of TNF- and IL-1 were analysed using ELISA assay kits obtained from INOVA laboratories (Catalogue No

It directly upregulates COL1A1, COL1A2, and COL3A1 at the mRNA level in human skin fibroblasts (quantified by qRT-PCR and northern blot), increases collagen protein synthesis (measured by [H]-proline incorporation into hydroxyproline-containing collagen peptides by Sircol assay), and promotes lysyl oxidase activity (copper-dependent cross-linking collagen fibrils for tensile strength)

Furthermore, the levels of GSH decreased with increased oxidative stress markers in the HFD-fed mice, which reflect the exhaustion of antioxidant potential and increased oxidative stress

Diagnostic value of quantitative hepatic copper determination in patients with Wilsons disease

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FXR-dependent modulation of the human small intestinal microbiome by the bile acid derivative obeticholic acid