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While classically depicted as four macromolecular IMM complexes working in a linear fashion to couple electron transfer with proton pumping, the respiratory chain is, in fact, a dynamic sink for many cellular redox reactions

These changes are also associated with the increased acetylation level of p53 and NF-B p65 and the enhancement in the expression of aging and inflammatory markers

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Nuclear-localized, iron-bound superoxide dismutase-2 antagonizes epithelial lineage programs to promote stemness of breast cancer cells via a histone demethylase activity

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The authors claimed complete normalization of sleep disturbances in the four insomniacs attributed to DSIP treatment