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Cosmetic applications , They are used as anti-wrinkle treatments to relax facial muscles, thereby reducing the appearance of fine lines and wrinkles, specifically in areas such as the forehead, around the eyes (crow's feet), between the eyebrows (glabellar lines), and around the mouth (Smoker lines)

Immune checkpoint molecules, such as cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and programmed death-1 (PD-1), play crucial roles by downregulating co-stimulatory signals [369] and maintaining Treg stability [370]

Microfocused ultrasound in regenerative aesthetics: a narrative review on mechanisms of action and clinical outcomes

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It also can be a little irritating to sensitive skin at times, so you may want to test it out on a small patch of skin before using it all over your body