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Instead, ergothioneine functions as an indirect antioxidant by activating cellular defense pathways. This challenges earlier assumptions about how ergothioneine provides its benefits

Key handling errors that can cause problems include: Shaking the vial vigorously during reconstitution, which denatures the peptide Using sterile water instead of bacteriostatic water, which lacks preservatives and allows bacterial growth Storing reconstituted peptide at room temperature instead of refrigerated Leaving the vial exposed to light, which degrades photosensitive amino acids Using reconstituted peptide beyond its stability window, typically 3-4 weeks Properly handled AOD 9604 should be clear and colorless in solution

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NICE guidelines (NG28) recommend regular blood glucose monitoring during treatment transitions to prevent hyperglycaemia and ensure metabolic stability