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Published July 1, 2013.

2,3 Correction of deficiency different routes of administration Depending on the cause of the deficiency, different strategies to correct it can be applied, although in conventional medical practice the most common treatment is intramuscular (i.m.) injection of B12

Those plaques, which vary in size, can crack and bleed, the Mayo Clinic says, or cause other symptoms like stiff joints, or burning or thickened nails

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Neurological manifestations include developmental delay, psychomotor retardation, behavioral abnormalities, ataxia, peripheral neuropathy, and seizures