oral semaglutide cardiovascular benefit 50 mg of #semaglutide daily was associated with body weight reduction and improved cardiometabolic risk factors in East Asian adults with overweight or #obesity, with or without type 2 #diabetes. https://ja.ma/41sPiYj Oral Semaglutide Shows Robust Glycemic

Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity. Proc Natl Acad Sci U S A

It supports biological pathways associated with GLP-1 regulation

Several animal studies have further shown that administration of GLP-1RAs, before or shortly after experimentally-induced stroke, increased angiogenesis, neurogenesis and cerebral blood flow (CBF), reduced neuroinflammation, oxidative stress, excitotoxicity, BBB leakage and apoptosis, and induced dose-dependent decreases in infarct volume [60,61,62]

Two patients on the same GLP-1 dose could both lose 7% body weight, yet one appears slimmer in the torso while the other sees more reduction in leg circumference

These were early-stage studies of BPC-157 as a cytoprotective agent for ulcerative colitis, and they were never completed to approval

Tolentino MJ, Miller JW, Gragoudas ES, et al