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48 Similar results were obtained in a hGLP-1R knock-in murine model in which the administration of Danuglipron resulted in an overall improvement of glucose tolerance and food intake reduction, thus opening the possibility to use an effective oral GLP-1RA

10.1038/s41392-024-01931-z Summary Keywords glucagon-like peptide-1 receptor, diabetes mellitus, -cell, insulin secretion, blood glucose Citation Li S, Huang N, Wang M, Huang W, Luo Y and Huang J (2025) GLP-1R in diabetes mellitus: from basic discovery to therapeutics development

In animal models of mania, liraglutide augmented the activity of the mood stabilizers sodium valproate 156 and lithium 157

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But I also remind each of them that no medication GLP-1s included replaces the foundational importance of nutrition, physical activity, sleep and mental health