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Previous studies have demonstrated that inhibition of CCL2 during chronic liver injury attenuates steatohepatitis by reducing hepatic monocyte and macrophage infiltration

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Bevacizumab was the first anti-angiogenic drug used in patients with RCC, followed by VEGFR inhibitors such as sunitinib, sorafenib, pazopanib, cabozantinib, and axitinib (101)