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The SNX protein family commonly features two specialized functional domains: a BAR (Bin/amphiphysin/Rvs) domain, which enables membrane curvature, and a PX (phox homology) domain, which binds to phosphoinositides

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The wrinkles, the thinning, the loss of density and resilience that we associate with aging skin are not entirely inevitable they're partly the consequence of losing this molecule

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Iron overload in the intestines leads to ROS accumulation and cell ferroptosis, which may be a pathogenic mechanism in colitis [269]

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