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Animal studies have shown that GLP-1 receptors are present on bone cells, including osteoblasts and osteoclasts, suggesting a potential direct effect on bone metabolism, though the clinical relevance in humans remains uncertain

The risk of MALO in patients with chronic liver diseases and type 2 diabetes was lower if they initiated a GLP1 agonist and adhered to this treatment over time, Wester and colleagues wrote

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doi: 10.3389/fimmu.2022.905423 200 HobeikaCMukkalaANWangKPollmannNGaneshSCalderon NovoaFet al

nor-NOHA (Table 1) weakens the inhibition of MDSC on T-cell proliferation and tumor cell metastasis in breast cancer (Secondini et al., 2017)

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