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However, it is crucial to consult with a healthcare provider before considering this option, as GLP-1s are prescription medications with specific indications and potential side effects

In contrast, excessive or sustained activation of TLRs can promote chronic inflammation and has been implicated in the pathogenesis of numerous immune-mediated disorders (262)

One trial explored the impact of combining dapagliflozin with the GLP-1 analogue exenatide in obese participants without diabetes, finding a mean weight loss 4.5 kg over 24 weeks [65]

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To achieve sustainable weight loss, many individuals benefit from a structured, personalized program that addresses metabolic health from multiple angles