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Sterne JA, Hernn MA, Reeves BC, Savovi J, Berkman ND, Viswanathan M, et al

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Pivalate-generating prodrugs and carnitine homeostasis in man

By dispersing ICG molecules at the single-molecule level within the COF structure, this system effectively prevents ICG aggregation and quenching, thereby greatly improving its phototherapeutic performance

Based on the available data, these drugs are great as adjunct OSA treatments, which include CPAP therapy for most patients. Tirzepatide significantly improved OSA outcomes, with concomitant reduction in body weight, compared with placebo in the SURMOUNT-OSA study