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Moreover, existing evidence demonstrated that inhibiting the phosphorylation of PI3K could increase AQP4 expression, which suggested that PI3K/Akt involves in the regulation of AQP4 (Song et al., 2018)

Blood glucose levels were reduced in bilirubin treated mice from 193.5 37.1 mg/dl to 112.2 8.9 mg/dl (Fig

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