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Ethical principles of the study complied with the European Directive 010/63/E, the Law on Amendments to the Animal Protection Act (Official Gazette 37/13), the Animal Protection Act (Official Gazette 135/06), the ordinance on the protection of animals used for scientific purposes (Official Gazette 55/13), Federation of European Laboratory Animal Science Associations (FELASA) recommendations, and the recommendations of the Ethics Committee of the School of Medicine, University of Zagreb

At the end of the study, the results showed significant improvements in plasma insulin and insulin resistance in this group compared to the placebo arm 43

Supplied individually at 5mg, they offer researchers the flexibility to run independent concentration-controlled experiments for each compound, side-by-side monotherapy comparison studies, and custom-ratio combination assays enabling a far broader range of experimental designs than a pre-blended stack format allows

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